sisalPronunciation: /ˈsʌɪs(ə)l/Definition of sisal noun [mass noun] a Mexican agave with large fleshy leaves, cultivated for fibre production. Agave sisalana, family Agavaceae the fibre made from the sisal plant, used especially for ropes or matting. Origin: mid 19th century: from Sisal, the name of a port in Yucatán, Mexicosisal in other Oxford dictionaries Definition of sisal in the US English dictionary