serotoninPronunciation: /ˌsɛrəˈtəʊnɪn/Translate serotonin | into Italian Definition of serotonin noun Biochemistry a compound present in blood platelets and serum, which constricts the blood vessels and acts as a neurotransmitter. Alternative name: 5-hydroxytryptamine; chemical formula: C10H12N2O Origin: 1940s: from serum + tonic + -in1serotonin in other Oxford dictionaries Definition of serotonin in the US English dictionary