segregationPronunciation: /ˌsɛgrɪˈgeɪʃ(ə)n/Translate segregation | into French | into German | into Italian | into Spanish Definition of segregation noun 1 [mass noun] the action or state of setting someone or something apart from others:the segregation of pupils with learning difficulties the enforced separation of different racial groups in a country, community, or establishment:an official policy of racial segregation 2 Genetics the separation of pairs of alleles at meiosis and their independent transmission via separate gametes. Derivatives segregational adjective segregationist adjective & noun (in the racial sense)segregation in other Oxford dictionaries Definition of segregation in the US English dictionary