sarcolemmaPronunciation: /ˈsɑːkəʊˌlɛmə/Definition of sarcolemma noun Physiology the fine transparent tubular sheath which envelops the fibres of skeletal muscles. Derivatives sarcolemmal adjective Origin: mid 19th century: from Greek sarx, sark- 'flesh' + lemma 'husk'sarcolemma in other Oxford dictionaries Definition of sarcolemma in the US English dictionary