reserpinePronunciation: /rɪˈsəːpiːn/Definition of reserpine noun [mass noun] Medicine a compound of the alkaloid class obtained from Indian snakeroot and other plants and used in the treatment of hypertension. Origin: 1950s: from the modern Latin species name R(auwolfia) serp(entina), named after Leonhard Rauwolf (see rauwolfia), + -ine4reserpine in other Oxford dictionaries Definition of reserpine in the US English dictionary