quinacrinePronunciation: /ˈkwɪnəkriːn, -krɪn/Definition of quinacrine noun [mass noun] Medicine a synthetic compound derived from acridine, used as an anthelmintic and antimalarial drug. (in full quinacrine mustard) Biochemistry a nitrogen mustard derived from quinacrine, used as a fluorescent stain for chromosomes. Origin: 1930s: blend of quinine and acridinequinacrine in other Oxford dictionaries Definition of quinacrine in the US English dictionary