prurigoPronunciation: /prʊəˈrʌɪgəʊ/Definition of prurigo noun [mass noun] Medicine a chronic skin disease causing severe itching. Derivatives pruriginousPronunciation: /prʊəˈrɪdʒɪnəs/ adjective Origin: mid 17th century: from Latin, from prurire 'to itch'prurigo in other Oxford dictionaries Definition of prurigo in the US English dictionary