prosopagnosiaPronunciation: /ˌprɒsə(ʊ)pagˈnəʊsɪə, -ˈnəʊzɪə/Definition of prosopagnosia noun [mass noun] Psychiatry the inability to recognize the faces of familiar people, typically as a result of damage to the brain. Origin: 1950s: modern Latin, from Greek prosōpon 'face' + agnōsia 'ignorance'prosopagnosia in other Oxford dictionaries Definition of prosopagnosia in the US English dictionary