pronucleusPronunciation: /prəʊˈnjuːklɪəs/Definition of pronucleus noun (plural pronuclei) Biology either of a pair of gametic nuclei, in the stage following meiosis but before their fusion leads to the formation of the nucleus of the zygote. Derivatives pronuclear adjective pronucleus in other Oxford dictionaries Definition of pronucleus in the US English dictionary