probenecidPronunciation: /prəʊˈbɛnɪsɪd/Definition of probenecid noun [mass noun] Medicine a synthetic sulphur-containing compound which promotes increased excretion of uric acid and is used to treat gout. Origin: 1950s: from pro(pyl) + ben(zoic) + -e- + (a)cidprobenecid in other Oxford dictionaries Definition of probenecid in the US English dictionary