prebioticPronunciation: /ˌpriːbʌɪˈɒtɪk/Definition of prebiotic adjective 1existing or occurring before the emergence of life. 2promoting the growth of beneficial intestinal microorganisms. noun a non-digestible food ingredient that promotes the growth of beneficial microorganisms in the intestines. prebiotic in other Oxford dictionaries Definition of prebiotic in the US English dictionary