ploidyPronunciation: /ˈplɔɪdi/Definition of ploidy noun [mass noun] Genetics the number of sets of chromosomes in a cell, or in the cells of an organism: [as modifier]:ploidy levelsOrigin: 1940s: from words such as (di)ploidy and (poly)ploidyploidy in other Oxford dictionaries Definition of ploidy in the US English dictionary