phosphatidylcholinePronunciation: /fɒsˌfatɪdʌɪlˈkəʊliːn/Definition of phosphatidylcholine noun [mass noun] Biochemistry a substance widely distributed in animal tissues, egg yolk, and some higher plants, consisting of phospholipids linked to choline. phosphatidylcholine in other Oxford dictionaries Definition of phosphatidylcholine in the US English dictionary