phenylbutazonePronunciation: /ˌfiːnʌɪlˈbjuːtəzəʊn, ˌfɛnɪl-/Definition of phenylbutazone noun [mass noun] a synthetic compound used as an analgesic drug in veterinary medicine. Origin: 1950s: from phenyl + but(yl) + azo- + -onephenylbutazone in other Oxford dictionaries Definition of phenylbutazone in the US English dictionary