peroxisomePronunciation: /pəˈrɒksɪsəʊm/Definition of peroxisome noun Biology a small organelle present in the cytoplasm of many cells, which contains the reducing enzyme catalase and usually some oxidases. Derivatives peroxisomalPronunciation: /-ˈsəʊm(ə)l/ adjective Origin: 1960s: from peroxide + -some3peroxisome in other Oxford dictionaries Definition of peroxisome in the US English dictionary