pancytopeniaPronunciation: /ˌpansʌɪtə(ʊ)ˈpiːniə/Definition of pancytopenia noun [mass noun] Medicine deficiency of all three cellular components of the blood (red cells, white cells, and platelets). Origin: 1940s: from pan- 'all' + cyto- 'cell' + Greek penia 'poverty, lack'pancytopenia in other Oxford dictionaries Definition of pancytopenia in the US English dictionary