orthognathousPronunciation: /ˌɔːθəgˈneɪθəs, ɔːˈθɒgnəθəs/Definition of orthognathous adjective Anatomy (especially of a person) having a jaw which does not project forwards and a facial angle approaching a right angle. Origin: mid 19th century: from ortho- 'straight' + Greek gnathos 'jaw' + -ousorthognathous in other Oxford dictionaries Definition of orthognathous in the US English dictionary