nucleosynthesisPronunciation: /ˌnjʊːklɪəʊˈsɪnθɪsɪs/Definition of nucleosynthesis noun [mass noun] Astronomy the cosmic formation of atoms more complex than the hydrogen atom. Derivatives nucleosyntheticPronunciation: /-ˈθɛtɪk/ adjective nucleosynthesis in other Oxford dictionaries Definition of nucleosynthesis in the US English dictionary