nuclearPronunciation: /ˈnjuːklɪə/Translate nuclear | into French | into German | into Italian | into Spanish Definition of nuclear adjective 1relating to the nucleus of an atom: nuclear chemistry denoting, relating to, or powered by the energy released in nuclear fission or fusion:nuclear submarines denoting, possessing, or involving weapons using nuclear energy:nuclear warheads a nuclear attack 2 Biology relating to the nucleus of a cell:nuclear DNAOrigin: mid 19th century: from nucleus + -ar1nuclear in other Oxford dictionaries Definition of nuclear in the US English dictionary