neutropeniaPronunciation: /ˌnjuːtrə(ʊ)ˈpiːniə/Definition of neutropenia noun [mass noun] Medicine the presence of abnormally few neutrophils in the blood, leading to increased susceptibility to infection. Derivatives neutropenic adjective Origin: 1930s: from neutral + Greek penia 'poverty, lack'neutropenia in other Oxford dictionaries Definition of neutropenia in the US English dictionary