myocardiumPronunciation: /ˌmʌɪə(ʊ)ˈkɑːdɪəm/Definition of myocardium noun [mass noun] Anatomy the muscular tissue of the heart. Derivatives myocardial adjective Origin: late 19th century: modern Latin, from myo- 'muscle' + Greek kardia 'heart'myocardium in other Oxford dictionaries Definition of myocardium in the US English dictionary