methylatePronunciation: /ˈmɛθɪleɪt/Definition of methylate verb [with object] (often as adjective methylated) mix or impregnate with methanol or methylated spirit: a portable stove which burned methylated briquettes Chemistry introduce a methyl group into (a molecule or compound): the cytosine moiety in the chromosomal DNA is usually methylatedDerivatives methylationPronunciation: /-ˈleɪʃ(ə)n/ noun methylate in other Oxford dictionaries Definition of methylate in the US English dictionary