manicPronunciation: /ˈmanɪk/Translate manic | into French | into Italian | into Spanish Definition of manic adjective (in psychiatry) relating to or affected by mania: the manic interludes in depression manic patients showing wild, apparently deranged, excitement and energy:a manic grin frantically busy; hectic:the pace is utterly manicDerivatives manically adverb manic in other Oxford dictionaries Definition of manic in the US English dictionary