maleficPronunciation: /məˈlɛfɪk/Definition of malefic adjective literary causing harm or destruction, especially by supernatural means: she was hypnotized by the spider’s malefic eyes Astrology relating to the planets Saturn and Mars, traditionally considered to have an unfavourable influence. Derivatives maleficence noun maleficent adjective Origin: mid 17th century: from Latin maleficus, from male 'ill' + -ficus 'doing'malefic in other Oxford dictionaries Definition of malefic in the US English dictionary