mailerPronunciation: /ˈmeɪlə(r)/Definition of mailer noun 1North American the sender of a letter or package by post: mailers of Christmas cards a person employed to dispatch newspapers or periodicals by post: walkouts by mailers and pressmen at the newspaper continued a free advertising pamphlet or catalogue sent by post: the coupons will be included in newspaper inserts and mailers a container used for conveying items by post: they didn’t fill in their name and address on the mailer 2 Computing a program that sends email messages. mailer in other Oxford dictionaries Definition of mailer in the US English dictionary