maculaPronunciation: /ˈmakjʊlə/Definition of macula noun (plural maculae /-liː/) another term for macule. (also macula lutea /ˈluːtɪə/) (plural maculae luteae /-tɪiː/) Anatomy an oval yellowish area surrounding the fovea near the centre of the retina in the eye, which is the region of keenest vision. Origin: late Middle English: from Latinmacula in other Oxford dictionaries Definition of macula in the US English dictionary