lithiasisPronunciation: /lɪˈθʌɪəsɪs/Definition of lithiasis noun [mass noun] Medicine the formation of stony concretions (calculi) in the body, most often in the gall bladder or urinary system. Origin: mid 17th century: from medieval Latin, based on Greek lithos 'stone'lithiasis in other Oxford dictionaries Definition of lithiasis in the US English dictionary