karyotypePronunciation: /ˈkarɪə(ʊ)tʌɪp/Definition of karyotype noun Biology & Medicine the number and visual appearance of the chromosomes in the cell nuclei of an organism or species. Derivatives karyotypicPronunciation: /-əˈtɪpɪk/ adjective karyotype in other Oxford dictionaries Definition of karyotype in the US English dictionary