isooctanePronunciation: /ˌʌɪsəʊˈɒkteɪn/Definition of isooctane noun [mass noun] Chemistry a liquid hydrocarbon present in petroleum. It serves as a standard in the system of octane numbers. Chemical formula: (CH3)3CCH2CH(CH3)CH3 isooctane in other Oxford dictionaries Definition of isooctane in the US English dictionary