irritantPronunciation: /ˈɪrɪt(ə)nt/Translate irritant | into German | into Italian | into Spanish Definition of irritant noun 1a substance that causes slight inflammation or other discomfort to the body: a powerful skin irritant 2a thing that is continually annoying or distracting:in 1966 Vietnam was becoming an irritant to the government adjective causing slight inflammation or other discomfort to the body: chlorine bleaches can be irritant to the skinDerivatives irritancy noun irritant in other Oxford dictionaries Definition of irritant in the US English dictionary