interleukinPronunciation: /ˌɪntəˈluːkɪn/Definition of interleukin noun Biochemistry any of a class of glycoproteins produced by leucocytes for regulating immune responses. Origin: 1970s: from inter- 'occurring between' + leukocyte (variant of leucocyte) + -in1interleukin in other Oxford dictionaries Definition of interleukin in the US English dictionary