hypoxanthinePronunciation: /ˌhʌɪpəʊˈzanθiːn/Definition of hypoxanthine noun [mass noun] Biochemistry a compound which is an intermediate in the metabolism of purines in animals and occurs in plant tissues. Alternative name: 6-hydroxypurine; chemical formula: C5H4N4O hypoxanthine in other Oxford dictionaries Definition of hypoxanthine in the US English dictionary