honeydewPronunciation: /ˈhʌnɪdjuː/Definition of honeydew noun 1 [mass noun] a sweet, sticky substance excreted by aphids and often deposited on leaves and stems. literary an ideally sweet substance. 2 (also honeydew melon) a melon of a variety with smooth pale skin and sweet green flesh. honeydew in other Oxford dictionaries Definition of honeydew in the US English dictionary