handcuffPronunciation: /ˈhan(d)kʌf/Translate handcuff | into German | into Spanish Definition of handcuff noun (handcuffs) a pair of lockable linked metal rings for securing a prisoner’s wrists. verb [with object] put handcuffs on (someone):he was led into court handcuffed to a policemanhandcuff in other Oxford dictionaries Definition of handcuff in the US English dictionary