guanacoPronunciation: /gwəˈnɑːkəʊ/Definition of guanaco noun (plural guanacos) a wild Andean mammal similar to the domestic llama, which is probably derived from it. It has a valuable pale brown pelt. Lama guanicoe, family Camelidae Origin: early 17th century: via Spanish from Quechua huanacuguanaco in other Oxford dictionaries Definition of guanaco in the US English dictionary