glycolysisPronunciation: /glʌɪˈkɒlɪsɪs/Definition of glycolysis noun [mass noun] Biochemistry the breakdown of glucose by enzymes, releasing energy and pyruvic acid. Derivatives glycolyticPronunciation: /ˌglʌɪkəˈlɪtɪk/ adjective glycolysis in other Oxford dictionaries Definition of glycolysis in the US English dictionary