glandersPronunciation: /ˈglandəz/Definition of glanders noun [usually treated as singular] a rare contagious disease that mainly affects horses, characterized by swellings below the jaw and mucous discharge from the nostrils. Glanders is caused by the bacterium Pseudomonas mallei Origin: late 15th century: from Old French glandre (see gland1)glanders in other Oxford dictionaries Definition of glanders in the US English dictionary