gigantismPronunciation: /ˈdʒʌɪgantɪz(ə)m, dʒʌɪˈgantɪz(ə)m/Definition of gigantism noun [mass noun] chiefly Biology unusual or abnormal largeness. Medicine excessive growth due to hormonal imbalance. Botany excessive size in plants due to polyploidy. gigantism in other Oxford dictionaries Definition of gigantism in the US English dictionary