gentamicinPronunciation: /ˌdʒɛntəˈmʌɪsɪn/Definition of gentamicin noun [mass noun] a broad-spectrum antibiotic used chiefly for severe systemic infections. This antibiotic is derived from bacteria of the genus Micromonospora Origin: 1960s: from genta- (of unknown origin) + -micin (alteration of -mycin)gentamicin in other Oxford dictionaries Definition of gentamicin in the US English dictionary