gemmulePronunciation: /ˈdʒɛmjuːl/Definition of gemmule noun Zoology a tough-coated dormant cluster of embryonic cells produced by a freshwater sponge for development in more favourable conditions. Derivatives gemmulation noun Origin: mid 19th century: from French, from Latin gemmula, diminutive of gemma 'bud, jewel'gemmule in other Oxford dictionaries Definition of gemmule in the US English dictionary