fibrinPronunciation: /ˈfʌɪbrɪn, ˈfɪb-/Definition of fibrin noun [mass noun] Biochemistry an insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood. Derivatives fibrinoid adjective fibrinous adjective Origin: early 19th century: from fibre + -in1fibrin in other Oxford dictionaries Definition of fibrin in the US English dictionary