epistemicPronunciation: /ˌɛpɪˈstiːmɪk, -ˈstɛm-/Definition of epistemic adjective relating to knowledge or to the degree of its validation. Derivatives epistemically adverb Origin: 1920s: from Greek epistēmē 'knowledge' (see epistemology) + -icepistemic in other Oxford dictionaries Definition of epistemic in the US English dictionary