epiduralPronunciation: /ˌɛpɪˈdjʊər(ə)l/Translate epidural | into French | into Italian Definition of epidural adjective Anatomy & Medicine on or around the dura mater, in particular (of an anaesthetic) introduced into the space around the dura mater of the spinal cord. noun an epidural anaesthetic, used especially in childbirth to produce loss of sensation below the waist. Origin: late 19th century: from epi- 'upon' + dura1 + -alepidural in other Oxford dictionaries Definition of epidural in the US English dictionary