ependymaPronunciation: /ɛˈpɛndɪmə/Definition of ependyma noun [mass noun] Anatomy the thin membrane of glial cells lining the ventricles of the brain and the central canal of the spinal cord. Derivatives ependymal adjective Origin: late 19th century: from Greek ependuma, from ependuein 'put on over'ependyma in other Oxford dictionaries Definition of ependyma in the US English dictionary