enzooticPronunciation: /ˌɛnzəʊˈɒtɪk/Definition of enzootic adjective (of a disease) regularly affecting animals in a particular district or at a particular season: enzootic hepatitisCompare with epizootic, endemic (sense 1 of the adjective).Origin: late 19th century: from en-2 'within' + Greek zōion 'animal' + -icenzootic in other Oxford dictionaries Definition of enzootic in the US English dictionary