effluxPronunciation: /ˈɛflʌks/Definition of efflux noun [mass noun] technical the flowing out of a substance or particle: the same active efflux of sodium from the cytoplasm to the external medium material that is flowing out: the routing for the jet efflux also needs to be consideredOrigin: mid 16th century: from medieval Latin effluxus, from effluere 'flow out'efflux in other Oxford dictionaries Definition of efflux in the US English dictionary