drupePronunciation: /druːp/Definition of drupe noun 1 Botany a fleshy fruit with thin skin and a central stone containing the seed, e.g. a plum, cherry, almond, or olive. 2a small marine mollusc with a thick knobbly shell, found mainly in the Indo-Pacific. Genus Drupa, family Muricidae, class Gastropoda Derivatives drupaceous adjective sense 1.Origin: mid 18th century: from Latin drupa 'overripe olive', from Greek druppa 'olive'drupe in other Oxford dictionaries Definition of drupe in the US English dictionary