depressorPronunciation: /dɪˈprɛsə/Definition of depressor noun 1 Anatomy (also depressor muscle) a muscle whose contraction pulls down a part of the body. any of several specific muscles in the face: [followed by Latin genitive]:depressor anguli oris 2 Physiology a nerve whose stimulation results in a lowering of blood pressure. 3an instrument for pressing something down. depressor in other Oxford dictionaries Definition of depressor in the US English dictionary