dehydrocholesterolPronunciation: /diːˌhʌɪdrə(ʊ)kəˈlɛstərɒl/Definition of dehydrocholesterol noun [mass noun] Biochemistry a derivative of cholesterol present in the skin. It can be converted to cholecalciferol (vitamin D3) by the action of ultraviolet radiation. Chemical formula: C27H44O Origin: 1930s: from dehydro- 'that has lost hydrogen' + cholesteroldehydrocholesterol in other Oxford dictionaries Definition of dehydrocholesterol in the US English dictionary