cytosolPronunciation: /ˈsʌɪtə(ʊ)sɒl/Definition of cytosol noun [mass noun] Biology the aqueous component of the cytoplasm of a cell, within which various organelles and particles are suspended. Derivatives cytosolicPronunciation: /ˌsʌɪtəʊˈsɒlɪk/ adjective cytosol in other Oxford dictionaries Definition of cytosol in the US English dictionary